Diagnosis for H-Pylori by Various Staining Methods in Gastric Biopsy Specimens

نویسندگان

چکیده

Objective: To run a comparison between specificity, sensitivity, PPV (positive predictive value) (PPV) & NPV (negative of the three varied H. pylori detection methods used in study. Materials and Methods: It is retrospective descriptive study that was carried out at Histopathology wing Pathology Department, Sahiwal Medical College, Sahiwal. comprised entire cases gastritis which were histopathologically proven by using Hematoxylin Eosin, Giemsa Immunohistochemical stains on biopsies taken endoscopy sent from Gastroenterology Department Govt. Haji Abdul Qayyum Teaching Hospital, January 2020 to month December 2020. SPSS version 20 employed evaluate all received data. Results: Amongst 95 samples, IHC (Immunohistochemistry) ranked highest, displaying 100% positive value 94.74% sensitivity. The H&E stain followed IHC, 94.44% specificity sensitivity respectively. runner up, 95.65% 94.12% Conclusions: Histologically, infection associated more with chronic active as compared gastritis. dissimilar staining achieved negative values equally well. precise method for H.Pylori gastric high specificity. suggested use than one where H.pylori level low, it will minimize false-negative rate. Keywords: Helicobacter pylori, Diagnosis, Staining, H& E,

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ژورنال

عنوان ژورنال: Pakistan Journal of Medical and Health Sciences

سال: 2022

ISSN: ['1996-7195']

DOI: https://doi.org/10.53350/pjmhs22165290